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DNA Structure and Replication

DNA Structure and Replication
What is the main damaging effect of UV radiation on DNA?

Dehydration
Formation of thymine dimers
Single strand break
Depurination

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DNA Structure and Replication
E.coli DNA polymerases II and III lack

5' → 3' exonuclease activity
5' → 3' endonuclease activity
partially 5' → 3' exonuclease activity
partially 5' → 3' endonuclease activity

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DNA Structure and Replication
What is the only common methylation in the DNA of eukaryotes?

None of these
Adenosine in GpA dinucleotides
Guanosine in ApGpA trinucleotides
Cytosine in CpG dinucleotides

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DNA Structure and Replication
The role of primase is to

proofread base pairing
synthesize an RNA primer to begin the elongation process
dismantle RNA primer
cleave and unwinds short sections of DNA ahead of the replication fork

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DNA Structure and Replication
The 5' and 3' numbers are related to the

length of the DNA strand
the base pair rule
the number of phosphates
carbon number in sugar

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DNA Structure and Replication
In a cesium chloride gradient, DNA labeled with 15N and centrifuged will form a band

below DNA containing 14N
all of these
with 14N-containing DNA
above DNA containing 14N

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