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Structure and Properties of Peptides

Structure and Properties of Peptides
Which hemoglobin chain replaces the beta chain in embryonic hemoglobulin?

Alfa
Epsilon
Delta
Gamma

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Structure and Properties of Peptides
In β-pleated sheet structures neighbouring

neighboring residues are hydrogen bonded
chains lie in a flat plane
neighboring chains are hydrogen bonded
neighboring chains are connected by a-helices

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Structure and Properties of Peptides
The oxygen in hemoglobin and myoglobin is bound to

lysine residues in the protein
the iron atom in the heme group
histidine residues in the protein
the nitrogen atoms on the heme

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Structure and Properties of Peptides
In the β-pleated sheet

adjacent polypeptide chains can either be parallel or antiparallel
All of these
the polypeptide chain is fully extended
hydrogen bonds are formed between the peptide bonds

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Structure and Properties of Peptides
The heme is held in place by a bond between

the Fe2+ and cysteine
the Fe3+ and histidine
the Fe2+ and histidine
the Fe3+ and cysteine

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Structure and Properties of Peptides
The peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala, was digested with cyanogen bromide (CNBr) to produce:

Val-Lys-Glu-Met + Ser-Trp-Arg-Ala
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala
Val-Lys-Glu + Met-Ser-Trp-Arg-Ala

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