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Structure and Properties of Peptides

Structure and Properties of Peptides
Which hemoglobin chain replaces the beta chain in embryonic hemoglobulin?

Epsilon
Delta
Gamma
Alfa

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

are equivalent to the (3-sheet structure
also have a cis geometry in their peptide bonds
have Y = F = 180°
do not occur in nature

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Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

dimeric proteins
intracellular proteins
hydrophobic proteins
extracellular proteins

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Structure and Properties of Peptides
Hydrogen bonds in a-helices are

more numerous than Vander Waals interactions
analogous to the steps in a spiral staircase
not present at Phe residues
roughly parallel to the helix axis

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

No effect on oxygen affinity
Increase in oxygen affinity
Increase affinity in muscle cell otherwise decrease
Decrease in oxygen affinity

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Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

collagen
globular proteins
silk protein
fibrous proteins

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