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Structure and Properties of Peptides

Structure and Properties of Peptides
Which hemoglobin chain replaces the beta chain in embryonic hemoglobulin?

Gamma
Delta
Epsilon
Alfa

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Structure and Properties of Peptides
When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about

0.5
0.1
0.9
1.7

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Pancreatic ribonuclease
Lysozyme
Myoglobin
Pancreatic DNase

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

do not occur in nature
also have a cis geometry in their peptide bonds
are equivalent to the (3-sheet structure
have Y = F = 180°

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Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

dimeric proteins
extracellular proteins
hydrophobic proteins
intracellular proteins

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Structure and Properties of Peptides
In the β-pleated sheet

hydrogen bonds are formed between the peptide bonds
All of these
adjacent polypeptide chains can either be parallel or antiparallel
the polypeptide chain is fully extended

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