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ATP Synthesis and Fatty Acid Oxidation

ATP Synthesis and Fatty Acid Oxidation
Where the acyl-CoA formed in the cytosol is transported for oxidation?

Endoplasmic reticulum
Remains in cytosol
Mitochondrial matrix
Microsomes

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ATP Synthesis and Fatty Acid Oxidation
Long-chain fatty acids are oxidized step-wise in one carbon units starting from the

aliphatic end
none of these
both (a) and (b)
carboxyl end

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ATP Synthesis and Fatty Acid Oxidation
The maximum energy per gram on oxidization is yielded from

glycogen
fat
protein
starch

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ATP Synthesis and Fatty Acid Oxidation
The three identical b subunits of the F1, complex during ATP synthesis have

similar affinities for ADP and ATP
different affinities for ADP but not for ATP
different affinities for ATP and for ADP
different affinities for ATP but not for ADP

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ATP Synthesis and Fatty Acid Oxidation
Membrane potential and the proton gradient

are both required to make ATP
cancel one another when uncouplers are present
reinforce one another when respiratory inhibitors are present
are sufficient, separately, to make ATP from ADP + Pi;

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ATP Synthesis and Fatty Acid Oxidation
The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)

both (a) and (b)
is due to the subsequent hydrolysis of the product
applies only to even-chain fatty acids
make this activation reaction the committed step on the pathway

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