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ATP Synthesis and Fatty Acid Oxidation

ATP Synthesis and Fatty Acid Oxidation
Where the acyl-CoA formed in the cytosol is transported for oxidation?

Microsomes
Endoplasmic reticulum
Mitochondrial matrix
Remains in cytosol

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ATP Synthesis and Fatty Acid Oxidation
Membrane potential and the proton gradient

are sufficient, separately, to make ATP from ADP + Pi;
are both required to make ATP
reinforce one another when respiratory inhibitors are present
cancel one another when uncouplers are present

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ATP Synthesis and Fatty Acid Oxidation
The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)

is due to the subsequent hydrolysis of the product
applies only to even-chain fatty acids
both (a) and (b)
make this activation reaction the committed step on the pathway

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ATP Synthesis and Fatty Acid Oxidation
The maximum energy per gram on oxidization is yielded from

fat
starch
protein
glycogen

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ATP Synthesis and Fatty Acid Oxidation
Long-chain fatty acids are oxidized step-wise in one carbon units starting from the

both (a) and (b)
aliphatic end
none of these
carboxyl end

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ATP Synthesis and Fatty Acid Oxidation
The transport of acyl-CoA for oxidation using a shuttle involves formation of the intermediate

Acyl-coenzyme A
3 acetyl-CoA
None of these
acyl-carnitine

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