DNA Structure and Replication
The size of a linear DNA fragment in a gel can be estimated by

fluorescence in UV light
the time it takes the gel to run
comparison with a molecular weight standard such as Hind III digested phage lambda
the sedimentation coefficient

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DNA Structure and Replication
Taylor, Woods and Hughes labeled Vicia DNA by allowing new DNA synthesis in the presence of radioactive thymine. After DNA replication (S phase of the cell cycle), it was observed that

only one chromatid of a chromosome was labeled
both (a) and (b)
both chromatids of a chromosome were labeled
neither chromatid was labeled

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