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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The most selective antibiotics are those that interfere with the synthesis of

bacterial cell walls
bacterial RNA
bacterial DNA
bacterial plasma membrane

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

Alteration or lack of penicillin-binding proteins
All of these
Impermeability of cell envelope
Production of β-lactamases by bacteria

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Antimicrobial Chemotherapeutic Agents
Cephalosporins and Penicillins interfere with which of the following?

Cell wall synthesis
Protein synthesis
DNA function
Cell membrane function

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Antimicrobial Chemotherapeutic Agents
Chemotherapeutic agents must

All of these
leave unaltered the host's natural defense mechanisms
be able to come in contact with the parasite by penetrating the cells
prevent/destroy the activity of a parasite

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Antimicrobial Chemotherapeutic Agents
The antibiotics not clinically useful for Pseudomonas aeruginosa infection is

piperacillin
ceftazidime
aminoglycosides
trimethoprim-sulphamethoxazole

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

bind to and inactivate a bacterial protein
are inactivated by β-lactamase
inhibit the cross-linking of peptidoglycan
must be transported into the cytoplasm in order to act

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