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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The most selective antibiotics are those that interfere with the synthesis of

bacterial cell walls
bacterial DNA
bacterial plasma membrane
bacterial RNA

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Antimicrobial Chemotherapeutic Agents
Which of the following antibiotics can't be used for treatment of infections with β-lactamase-producing Staphylococcus aureus?

Vancomycin
Ampicillin/sulbactam
Piperacillin
Cephalothin

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Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

inhibit DNA synthesis
inhibit protein synthesis
inhibit folic acid synthesis
injury to the plasma membrane

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Antimicrobial Chemotherapeutic Agents
The larger the __________ , the better the chemotherapeutic agent.

therapeutic index
therapeutic dose
spectrum
selective toxicity

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Antimicrobial Chemotherapeutic Agents
Bacterial cells susceptible to penicillium can be protected from destruction if the medium in which they are exposed is of

moderate osmotic pressure
high osmotic pressure
low osmotic pressure
high surface tension

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Antimicrobial Chemotherapeutic Agents
With which of the following aminoglycosides interfere?

DNA function
Protein synthesis
Cell wall synthesis
Cell membrane function

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