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Protein and Nucleic Acid Interactions

Protein and Nucleic Acid Interactions
The enzyme that joins DNA cuts is called

DNA phosphorylase
joinase
ligase
reverse transcriptase

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Protein and Nucleic Acid Interactions
Different DNA polymerases play distinct roles in DNA replication and repair in both prokaryotic and eukaryotic cells. All known DNA polymerases synthesize DNA only in the __________ by the addition of dNTPs to a performed primer strand of DNA.

negative direction
5' to 3' direction
positive direction
3' to 5' direction

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Protein and Nucleic Acid Interactions
Which of the following amino acids interact with the DNA or RNA backbone (i.e. phosphate)?

Leu and Ala
Lys and Arg
Ile and Val
Cys and Met

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Protein and Nucleic Acid Interactions
Reverse transcripase from HIV does not

requires a primer
has a 5' to 3' polymerase activity
uses RNA as a template
has a 3'- 5' exonuclease activity

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Protein and Nucleic Acid Interactions
Cleavage of DNA by EcoRI endonuclease results in the formation of

one 3'-OH end and one 5'-phosphate end
two 3'-OH ends and two 5'-phosphate ends
one 3'-OH end and two 5'-phosphate end
two 3'-phosphate ends and two 3'-OH ends

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Protein and Nucleic Acid Interactions
Which of the following amino acids can interact with the DNA or RNA nucleotide bases via hydrogen bonding?

Asn and Gln
Ile and Val
Cys and Met
Lys and Leu

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