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Protein and Nucleic Acid Interactions

Protein and Nucleic Acid Interactions
Reverse transcripase from HIV does not

has a 3'- 5' exonuclease activity
requires a primer
uses RNA as a template
has a 5' to 3' polymerase activity

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Protein and Nucleic Acid Interactions
Which of the following amino acids can interact with the DNA or RNA nucleotide bases via hydrogen bonding?

Cys and Met
Lys and Leu
Ile and Val
Asn and Gln

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Protein and Nucleic Acid Interactions
Which of the following amino acids interact with the DNA or RNA backbone (i.e. phosphate)?

Leu and Ala
Cys and Met
Lys and Arg
Ile and Val

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Protein and Nucleic Acid Interactions
Different DNA polymerases play distinct roles in DNA replication and repair in both prokaryotic and eukaryotic cells. All known DNA polymerases synthesize DNA only in the __________ by the addition of dNTPs to a performed primer strand of DNA.

positive direction
5' to 3' direction
3' to 5' direction
negative direction

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Protein and Nucleic Acid Interactions
The enzyme that joins DNA cuts is called

joinase
DNA phosphorylase
ligase
reverse transcriptase

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Protein and Nucleic Acid Interactions
Cleavage of DNA by EcoRI endonuclease results in the formation of

two 3'-phosphate ends and two 3'-OH ends
two 3'-OH ends and two 5'-phosphate ends
one 3'-OH end and one 5'-phosphate end
one 3'-OH end and two 5'-phosphate end

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