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STRUCTURE AND PROPERTIES OF PEPTIDES

Structure and Properties of Peptides
An oil drop with a polar coat is a metaphor referring to the three dimensional structure of

fibrous proteins
silk protein
globular proteins
collagen

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Lysozyme
Pancreatic ribonuclease
Pancreatic DNase
Myoglobin

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Structure and Properties of Peptides
In β-pleated sheet structures neighbouring

neighboring chains are connected by a-helices
chains lie in a flat plane
neighboring chains are hydrogen bonded
neighboring residues are hydrogen bonded

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.

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Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

intracellular proteins
extracellular proteins
hydrophobic proteins
dimeric proteins

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