Allosteric Effects Small molecules affect hemoglobin (Hb) by increasing [H+] and decreasing Hb affinity for O2 increasing [H+] decreasing Hb affinity for O2 increasing Hb affinity for O2 increasing [H+] and decreasing Hb affinity for O2 increasing [H+] decreasing Hb affinity for O2 increasing Hb affinity for O2 ANSWER DOWNLOAD EXAMIANS APP
Allosteric Effects When protein binds two ligands in a non-cooperative manner, then the x-intercept of the Scatchard Plot is not defined None of these 2 1 not defined None of these 2 1 ANSWER DOWNLOAD EXAMIANS APP
Allosteric Effects A protein that binds two ligands in a non-cooperative manner will show a hyperbolic binding curve a linear Scatchard Plot both (b) and (c) a sigmodial binding curve a hyperbolic binding curve a linear Scatchard Plot both (b) and (c) a sigmodial binding curve ANSWER DOWNLOAD EXAMIANS APP
Allosteric Effects The conformational changes from the T to the R state is initiated by movement of the F-helix, which contains the proximal His movement of the proximal histidine towards the heme reorganization of protein-protein contacts between the individual subunits binding of oxygen to the heme movement of the F-helix, which contains the proximal His movement of the proximal histidine towards the heme reorganization of protein-protein contacts between the individual subunits binding of oxygen to the heme ANSWER DOWNLOAD EXAMIANS APP
Allosteric Effects O2 binding to hemoglobin results in extensive protein conformational change 100-fold lower affinity for the last O2 bound than for the first 100-fold higher affinity for the last O2 bound than for the first both (a) and (b) extensive protein conformational change 100-fold lower affinity for the last O2 bound than for the first 100-fold higher affinity for the last O2 bound than for the first both (a) and (b) ANSWER DOWNLOAD EXAMIANS APP
Allosteric Effects An allosteric activator decreases the binding affinity increases the binding affinity stabilizes the R state of the protein both (a) and (c) decreases the binding affinity increases the binding affinity stabilizes the R state of the protein both (a) and (c) ANSWER DOWNLOAD EXAMIANS APP
EXAMIANS