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MONOCLONAL ANTIBODIES

Monoclonal Antibodies
Small simple molecules are

rich antigens
heterophilic antigens
poor antigens
moderate antigens

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Monoclonal Antibodies
The EBV-hybridoma technique

facilitates the proliferation of antigen specific B cells
All of these
gives much higher hybridization frequencies
immortalizes the donor Bcells

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Monoclonal Antibodies
Helper T cells assist in the functions of

certain B cells and other T cells
certain T cells
None of these
certain B cells

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Monoclonal Antibodies
In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

T4 cells are greatly reduced
T8 cells are greatly increased
T4 cells are greatly increased
T8 cells are greatly reduced

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Hybridization with a suitable lymphoid tumor cell
Transfection with tumor derived DNA
All of these
Transformation following infection by Epstein-Barr virus (EB V)

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