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ATP Synthesis and Fatty Acid Oxidation

ATP Synthesis and Fatty Acid Oxidation
How many molecules of acetyl-CoA are produced in oxidation of palmitic acid (C16), which involves seven rounds of oxidation?

8
6
7
9

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ATP Synthesis and Fatty Acid Oxidation
Where the acyl-CoA formed in the cytosol is transported for oxidation?

Endoplasmic reticulum
Microsomes
Remains in cytosol
Mitochondrial matrix

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ATP Synthesis and Fatty Acid Oxidation
The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)

make this activation reaction the committed step on the pathway
is due to the subsequent hydrolysis of the product
applies only to even-chain fatty acids
both (a) and (b)

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ATP Synthesis and Fatty Acid Oxidation
The oxidation of methanol (wood alcohol) in human retina tissue leads directly to the formation of

formaldehyde
sugars
CO2
none of these

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ATP Synthesis and Fatty Acid Oxidation
Long-chain fatty acids are oxidized step-wise in one carbon units starting from the

aliphatic end
both (a) and (b)
carboxyl end
none of these

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ATP Synthesis and Fatty Acid Oxidation
Each cycle of β-oxidation produces

1 FADH2, 1 NADH and 1 acetyl-CoA
1 FADH2, 1 NAD+, and 1 acetyl-CoA
1 FADH2, 1 NADH and 2 CO2 molecules
1 FAD, 1 NAD+ and 2 CO2 molecules

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