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DNA Sequencing, Mutation and Repair

DNA Sequencing, Mutation and Repair
Genetic variations are

influenced by the environment
temporary
stable
not heritable

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DNA Sequencing, Mutation and Repair
A nonsense mutation may result into

a large deletion within the reading frame of a gene
an abnormal elongation of a polypeptide
modification of mRNA
a premature termination of the synthesis of a polypeptide

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DNA Sequencing, Mutation and Repair
When mutations involve vital functions so that the mutants are nonviable, it is a

transversion
none of these
nonsense mutation
lethal mutation

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DNA Sequencing, Mutation and Repair
Which of these mechanisms for thymine dimers repair lead to mutations?

Excision repair
SOS repair
Never leads to mutation
Photoreactivation

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DNA Sequencing, Mutation and Repair
The promoter on an expression vector used to overproduce proteins in bacteria is

the natural promoter of the gene being cloned
a bacterial promoter
expressed both in bacteria and mammalian cells
not a regulated promoter

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DNA Sequencing, Mutation and Repair
Differentiation of four different bases in automated sequencing systems is that each base has

different radioactive tag
cytosine at start
unique antibody bound to it
distinctive fluorescent tag

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