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DNA Sequencing, Mutation and Repair

DNA Sequencing, Mutation and Repair
Genetic variations are

stable
influenced by the environment
not heritable
temporary

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DNA Sequencing, Mutation and Repair
A nonsense mutation introduced into the DNA sequence of a gene may

have no effect on the transcript or protein made
shorten the length of the protein encoded by the gene
cause premature termination of the mRNA
cause a shift in reading frame

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DNA Sequencing, Mutation and Repair
A nonsense mutation may result into

a large deletion within the reading frame of a gene
modification of mRNA
a premature termination of the synthesis of a polypeptide
an abnormal elongation of a polypeptide

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DNA Sequencing, Mutation and Repair
The promoter on an expression vector used to overproduce proteins in bacteria is

expressed both in bacteria and mammalian cells
a bacterial promoter
not a regulated promoter
the natural promoter of the gene being cloned

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DNA Sequencing, Mutation and Repair
Which of the following(s) is/are steps in excision repair mechanisms?

Incision
Excision
Ligation
All of these

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DNA Sequencing, Mutation and Repair
Which of the following bacterial genome was sequenced first?

S. pneumoniae
H. influenzae
S. thermophilus
E. coli

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