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DNA Sequencing, Mutation and Repair

DNA Sequencing, Mutation and Repair
Which of the following bacterial genome was sequenced first?

S. thermophilus
H. influenzae
S. pneumoniae
E. coli

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DNA Sequencing, Mutation and Repair
A nonsense mutation may result into

a premature termination of the synthesis of a polypeptide
a large deletion within the reading frame of a gene
an abnormal elongation of a polypeptide
modification of mRNA

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DNA Sequencing, Mutation and Repair
Which of these mechanisms for thymine dimers repair lead to mutations?

Never leads to mutation
Photoreactivation
Excision repair
SOS repair

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DNA Sequencing, Mutation and Repair
Frame shift mutation may occur as a result of

deamination of cytosine to uracil
None of these
conversion of guanine to xanthine
formation of a thymine-dimer

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DNA Sequencing, Mutation and Repair
The promoter on an expression vector used to overproduce proteins in bacteria is

expressed both in bacteria and mammalian cells
a bacterial promoter
not a regulated promoter
the natural promoter of the gene being cloned

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DNA Sequencing, Mutation and Repair
Which of the following mutations arise without exposure to external agents?

Spontaneous mutations
Analogous mutations
None of these
Induced mutations

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