Recombinant DNA
For gene probes to be useful they must

None of these
be labeled in some manner to allow detection
both (a) and (b)
be large enough to contain gene-specific sequences

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Recombinant DNA
Bacterial cells protect their own DNA from degradation by restriction endonucleases by

methylating the DNA at the sites that the enzyme recognizes
not producing any restriction endonucleases
having anti restriction endonucleases
deleting all recognition sites from the genome

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