Recombinant DNA
For gene probes to be useful they must

be large enough to contain gene-specific sequences
None of these
be labeled in some manner to allow detection
both (a) and (b)

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Recombinant DNA
The Southern blotting technique depends on

similarities between the sequences of probe RNA and experimental RNA
similarities between the sequences of probe protein and experimental protein
the molecular mass of proteins
similarities between the sequences of probe DNA and experimental DNA

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