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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

DNA function
cell wall synthesis
protein synthesis
cell membrane function

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Antimicrobial Chemotherapeutic Agents
The compound(s) which act(s) as metabolic antagonist is/are

trimethoprim
none of these
sulphonamides
both (a) and (b)

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Antimicrobial Chemotherapeutic Agents
Who developed the concept of specific toxicity?

Pasteur
Fleming
Watson
Ehrlich

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Antimicrobial Chemotherapeutic Agents
Which of the following drugs may show plasmid-mediated resistance?

Nalidixic acid
Methicillin
Ampicillin
Rifampicin

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

are inactivated by β-lactamase
inhibit the cross-linking of peptidoglycan
bind to and inactivate a bacterial protein
must be transported into the cytoplasm in order to act

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Antimicrobial Chemotherapeutic Agents
With which of the following aminoglycosides interfere?

Cell wall synthesis
DNA function
Cell membrane function
Protein synthesis

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