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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

protein synthesis
DNA function
cell wall synthesis
cell membrane function

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Antimicrobial Chemotherapeutic Agents
The penicillin stable in gastric acid and suitable for oral administration is

carbenicillin
closacillin
pencillin-G
methicillin

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Antimicrobial Chemotherapeutic Agents
Chelate forming peptide antibiotic are/is

vancomycin
both (a) and (b)
sideromycins
bleomycins

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

must be transported into the cytoplasm in order to act
are inactivated by β-lactamase
inhibit the cross-linking of peptidoglycan
bind to and inactivate a bacterial protein

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Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

inhibit protein synthesis
injury to the plasma membrane
inhibit folic acid synthesis
inhibit DNA synthesis

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Antimicrobial Chemotherapeutic Agents
A parenteral route of drug administration refers to

intravenously
intramuscularly
oral
nonoral

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