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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The nitrofurans differ from the antibiotics in that they

do not occur naturally
occur naturally
all of these
are antimicrobial drugs

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Antimicrobial Chemotherapeutic Agents
The larger the __________ , the better the chemotherapeutic agent.

therapeutic dose
spectrum
selective toxicity
therapeutic index

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Antimicrobial Chemotherapeutic Agents
Which is not an amino acid and peptide antibiotic?

Tetranactin
Bacitracin
Penicillin
Actinomycin

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Antimicrobial Chemotherapeutic Agents
Who developed the concept of specific toxicity?

Ehrlich
Pasteur
Watson
Fleming

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

are inactivated by β-lactamase
bind to and inactivate a bacterial protein
inhibit the cross-linking of peptidoglycan
must be transported into the cytoplasm in order to act

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Antimicrobial Chemotherapeutic Agents
Novobiocin can be used against

gram -ve Meningococci & Gonococci
gram +ve Staphylococci
all of these
Haemophilus

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