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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Who developed the concept of specific toxicity?

Fleming
Ehrlich
Pasteur
Watson

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Antimicrobial Chemotherapeutic Agents
Which of the following drugs may show plasmid-mediated resistance?

Rifampicin
Methicillin
Ampicillin
Nalidixic acid

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Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

inhibit folic acid synthesis
inhibit DNA synthesis
inhibit protein synthesis
injury to the plasma membrane

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Antimicrobial Chemotherapeutic Agents
Chemotherapeutic agents must

be able to come in contact with the parasite by penetrating the cells
leave unaltered the host's natural defense mechanisms
prevent/destroy the activity of a parasite
All of these

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Antimicrobial Chemotherapeutic Agents
Which of the following protein synthesis mechanisms may be affected by particular drugs?

Aminoacyl-tRNA binding
All of these
mRNA translocation
Peptide bond formation

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

inhibit the cross-linking of peptidoglycan
must be transported into the cytoplasm in order to act
bind to and inactivate a bacterial protein
are inactivated by β-lactamase

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