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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Which of the following drugs may show plasmid-mediated resistance?

Methicillin
Ampicillin
Rifampicin
Nalidixic acid

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Antimicrobial Chemotherapeutic Agents
Which of the following tests is used to determine the minimal lethal concentration?

All of these
Agar dilution test
Broth dilution test
Dilution susceptibility tests

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

bind to and inactivate a bacterial protein
inhibit the cross-linking of peptidoglycan
must be transported into the cytoplasm in order to act
are inactivated by β-lactamase

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Antimicrobial Chemotherapeutic Agents
Quinolones are

broad-spectrum
antimetabolites
bacteriostatic
penicillin derivatives

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Antimicrobial Chemotherapeutic Agents
Which of the following protein synthesis mechanisms may be affected by particular drugs?

Aminoacyl-tRNA binding
mRNA translocation
All of these
Peptide bond formation

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Antimicrobial Chemotherapeutic Agents
Which of the following antibiotics can't be used for treatment of infections with β-lactamase-producing Staphylococcus aureus?

Cephalothin
Piperacillin
Vancomycin
Ampicillin/sulbactam

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