Immune System
Which of the following(s) is/are the determinants of antigenicity?

Foreignness
All of these
Size of the antigen
Chemical nature

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Immune System
Which of the following statements is false regarding B cells?

B cells that recognize high concentrations of antigens (self) in the absence of other signals undergo apoptosis in the bone marrow
B one marrow stem cells migrate to the thymus and develop into B cells
B cells synthesize antibodies and put them on their cell surface
B cells can undergo class switching and produce a different antibody type

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Immune System
Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated?

Antibody proteins can physically change their shape to bind different epitopes
By the combination of different heavy and light chains that form the antigen binding site
Both (a) and (b)
By rearrangements of the DNA encoding the variable regions of the heavy and light chains

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