Immune System
Major Histo Compatibility Complex (MHC) is a collection of genes arrayed on

chromosome 17in man, chromosome 6 in mice
chromosome 6 in man, chromosone 21 in mice
chromosome 21 in man, chromosome 6 in mice
chromosome 6 in man, chromosome 17 in mice

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Immune System
The role of the M cell is to

pass bacteria or virus to underlying macrophages for processing and presentation of antigen
they use their cilia to propel mucus out of the small intestine
induce apoptosis in virus-infected small intestinal epithelia cells
trap virus in mucus and prevent entry

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Immune System
Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated?

By rearrangements of the DNA encoding the variable regions of the heavy and light chains
Both (a) and (b)
Antibody proteins can physically change their shape to bind different epitopes
By the combination of different heavy and light chains that form the antigen binding site

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Immune System
Which of the following statements is false regarding B cells?

B cells that recognize high concentrations of antigens (self) in the absence of other signals undergo apoptosis in the bone marrow
B cells can undergo class switching and produce a different antibody type
B one marrow stem cells migrate to the thymus and develop into B cells
B cells synthesize antibodies and put them on their cell surface

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Immune System
Polymorphonuclear leukocytes (or PMNs)

are a type of phagocyte that can engulf and kill bacteria
All of these
can be attracted to the site of an infection following activation of complement
are derived from bone marrow stem cells

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