Immune System
Major Histo Compatibility Complex (MHC) is a collection of genes arrayed on

chromosome 17in man, chromosome 6 in mice
chromosome 21 in man, chromosome 6 in mice
chromosome 6 in man, chromosome 17 in mice
chromosome 6 in man, chromosone 21 in mice

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Immune System
Which of the following statements is false regarding B cells?

B one marrow stem cells migrate to the thymus and develop into B cells
B cells that recognize high concentrations of antigens (self) in the absence of other signals undergo apoptosis in the bone marrow
B cells synthesize antibodies and put them on their cell surface
B cells can undergo class switching and produce a different antibody type

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Immune System
Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated?

By rearrangements of the DNA encoding the variable regions of the heavy and light chains
Antibody proteins can physically change their shape to bind different epitopes
By the combination of different heavy and light chains that form the antigen binding site
Both (a) and (b)

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