DNA Structure and Replication
What does ligase do during replication of DNA?

Joins nicks in DNA strands
Digests mRNA when it is no longer needed
Synthesizes the lagging strand
Makes copies of mRNA from DNA

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DNA Structure and Replication
In DNA, nucleotides are covalently joined together by

3', 4' phosphodiester bonds to form a repetitive sugar-phosphate chain
3', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain
2', 3' phosphodiester bonds to form a repetitive sugar-phosphate chain
2', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain

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