Transcription and Regulation
Transcription of each set of rRNA genes by RNA polymerasel produces

a single 28S rRNA precursor molecule
a single 18S rRNA precursor molecule
a single 5S rRNA precursor molecule
a single 45S rRNA precursor molecule

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Transcription and Regulation
Multiple copies of 5S genes, located at a chromosomal site distinct from the other rRNA genes

are transcribed by DNA polymerase I
are transcribed by rRNA polymerase I and the 5S rRNA
are transcribed by rRNA polymerase II
are transcribed by rRNA polymerase III and the 5S rRNA

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