Nucleic Acids
The glycosidic bonds in DNA and RNA

stabilize Watson-Crick H-bonds
connect the sugar to the base
are free to rotate over about 180°
can be hydrolyzed by OH- ion

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Nucleic Acids
Thymidine

can participate in hydrophobic interactions due to its methyl group
All of these
is replaced by uracil in RNA
normally forms two hydrogen bonds with adenosine

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