Nucleic Acids
The glycosidic bonds in DNA and RNA

connect the sugar to the base
stabilize Watson-Crick H-bonds
can be hydrolyzed by OH- ion
are free to rotate over about 180°

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Nucleic Acids
Thymidine

is replaced by uracil in RNA
can participate in hydrophobic interactions due to its methyl group
All of these
normally forms two hydrogen bonds with adenosine

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