Nucleic Acids
The unfavourable free energy associated with not satisfying a hydrogen bond after formation of the double helix is approximately

10 kJ/mol
30 kJ/mol
20 kJ/mol
25 kJ/mol

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Nucleic Acids
Thymidine

can participate in hydrophobic interactions due to its methyl group
All of these
normally forms two hydrogen bonds with adenosine
is replaced by uracil in RNA

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