The nucleophile in serine proteases is Asparagine Serine both (a) and (b) water TRUE ANSWER : ? YOUR ANSWER : ?
What is the specificity of the Clostripain protease? None of these It cleave after Arg residues It cleave after His residues It cleave after Lys residues TRUE ANSWER : ? YOUR ANSWER : ?
Before they can react, many molecules need to be destabilized. This state is typically achieved through changing the reaction from a biosynthetic to a catabolic pathway the input of a small amount of activation energy changing the three-dimensional shape of the molecule oxidizing the molecules by removing electrons TRUE ANSWER : ? YOUR ANSWER : ?
Common feature in all serine proteases is a hydrophilic specificity pocket hydrophobic specificity pocket cluster of reactive serine residues single reactive serine residue TRUE ANSWER : ? YOUR ANSWER : ?
The E.coli pyruvic acid dehydrogenase complex is reported to decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 TRUE ANSWER : ? YOUR ANSWER : ?
The cleavage specificity of trypsin and chymotrypsin depend in part on the absence of water in the active site size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket TRUE ANSWER : ? YOUR ANSWER : ?
The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site keep the specificity pocket open function as a proton shuttle neutralize the charge on the other's side chain TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following (s) is/are serine proteases? all of these Elastase Chymotrypsin Trypsin TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate TRUE ANSWER : ? YOUR ANSWER : ?
Which of the common features are shared between serine and aspartate proteases? Both use a base to activate the nucleophile All of these Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences TRUE ANSWER : ? YOUR ANSWER : ?