Combined cellular and humoral immune deficiencies result from lack of all of the following except HIV infection of CD4+ T cells transporter of antigen peptides (TAP) class II MHC a thymus TRUE ANSWER : ? YOUR ANSWER : ?
A selective IgA deficiency would be expected to result in problems with infections following dental work due to bacteria entering the bloodstream bacterial infections mucosal pathogens pathogens which can survive inside macrophages TRUE ANSWER : ? YOUR ANSWER : ?
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with dendritic cell activation to become a mature APC CTL killing of viruses infected cell processing of virus peptides macrophage intracellular killing of bacteria TRUE ANSWER : ? YOUR ANSWER : ?
Specific translocations are associated with breast cancer some leukemias pancreatic cancer colon cancer TRUE ANSWER : ? YOUR ANSWER : ?
X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be failure of Th2 cells to provide co-stimulation for B cell proliferation activation of B cells by T-independent antigens failure of Th2 cells to provide co-stimulation for B cell isotype switching failure of B cells to provide co-stimulation for Th2 activation TRUE ANSWER : ? YOUR ANSWER : ?
The chemical, typically released by the body in an allergic response is perforins antihistamines histamine allergens TRUE ANSWER : ? YOUR ANSWER : ?
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced alternative complement activation. IgG synthesis macrophage activation to vesicular pathogens CD8 T cell-mediated cytotoxicity TRUE ANSWER : ? YOUR ANSWER : ?
DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a recombinant mouse for CD3 knock-out mouse for a thymus nude mouse knock-out mouse for RAG-1 and RAG-2 TRUE ANSWER : ? YOUR ANSWER : ?
Which of the Rous sarcoma virus has a homologous cellular protein? v-src v-ha-ras v-ha-src c-src TRUE ANSWER : ? YOUR ANSWER : ?