MONOCLONAL ANTIBODIES QUIZ

T cells are the source of

interferon

all of these

lymphotoxin

interleukin

TRUE ANSWER : ?
YOUR ANSWER : ?

Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgG

IgA

IgE

Ig MAbs

TRUE ANSWER : ?
YOUR ANSWER : ?

Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

poor recognition of immunoglobulin, Ig constant regions

All of these

absence of human immune response against murine proteins (HAMA) response

presence of HAMA response

TRUE ANSWER : ?
YOUR ANSWER : ?

In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

T8 cells are greatly reduced

T4 cells are greatly reduced

T8 cells are greatly increased

T4 cells are greatly increased

TRUE ANSWER : ?
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The antigen-specific lymphocytes can be immortalized by which of the following method?

All of these

Transfection with tumor derived DNA

Hybridization with a suitable lymphoid tumor cell

Transformation following infection by Epstein-Barr virus (EB V)

TRUE ANSWER : ?
YOUR ANSWER : ?

Which type of cell actually secrets antibodies?

macrophages

dendritic cells

T cells

plasma cells

TRUE ANSWER : ?
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In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a

myeloma

natural killer cell

lymphoblast

hybridoma

TRUE ANSWER : ?
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The EBV-hybridoma technique

gives much higher hybridization frequencies

facilitates the proliferation of antigen specific B cells

All of these

immortalizes the donor Bcells

TRUE ANSWER : ?
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The primary B cell receptor is

IgE

IgG

IgA

IgD

TRUE ANSWER : ?
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Small simple molecules are

heterophilic antigens

moderate antigens

rich antigens

poor antigens

TRUE ANSWER : ?
YOUR ANSWER : ?