MONOCLONAL ANTIBODIES QUIZ

The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as

all of these

combination of EB Vand hybridoma techniques

hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes

transformation of antigen specific B lymphocytes (EBV)

TRUE ANSWER : ?
YOUR ANSWER : ?

The EBV-hybridoma technique

All of these

immortalizes the donor Bcells

facilitates the proliferation of antigen specific B cells

gives much higher hybridization frequencies

TRUE ANSWER : ?
YOUR ANSWER : ?

The primary B cell receptor is

IgD

IgA

IgG

IgE

TRUE ANSWER : ?
YOUR ANSWER : ?

In human B cells and T cells are matured in the

bone marrow and thymus respectively

bursa and thymus respectively

lymph nodes and spleen respectively

none of these

TRUE ANSWER : ?
YOUR ANSWER : ?

In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

T8 cells are greatly reduced

T4 cells are greatly increased

T8 cells are greatly increased

T4 cells are greatly reduced

TRUE ANSWER : ?
YOUR ANSWER : ?

TC cells are important in controlling

virus infections

all of these

allergy

autoimmunity

TRUE ANSWER : ?
YOUR ANSWER : ?

The Ig locus is about

2/3rd of all hybridomas

l/3rd of all hybridomas

1/4th of all hybridomas

l/2nd of all hybridomas

TRUE ANSWER : ?
YOUR ANSWER : ?

Helper T cells assist in the functions of

certain B cells

certain B cells and other T cells

certain T cells

None of these

TRUE ANSWER : ?
YOUR ANSWER : ?

A cytokine that stimulates the activity of B and T cells is

all of these

lymphotoxin

interlukin-2

interlukin-1

TRUE ANSWER : ?
YOUR ANSWER : ?

The antigen-specific lymphocytes can be immortalized by which of the following method?

Transfection with tumor derived DNA

Hybridization with a suitable lymphoid tumor cell

All of these

Transformation following infection by Epstein-Barr virus (EB V)

TRUE ANSWER : ?
YOUR ANSWER : ?