MONOCLONAL ANTIBODIES QUIZ

bacteria

a hapten

protein

virus

IgG

IgA

IgD

IgE

transformation of antigen specific B lymphocytes (EBV)

combination of EB Vand hybridoma techniques

hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes

all of these

T4 cells are greatly reduced

T8 cells are greatly reduced

T4 cells are greatly increased

T8 cells are greatly increased

None of these

certain T cells

certain B cells

certain B cells and other T cells

Transformation following infection by Epstein-Barr virus (EB V)

All of these

Hybridization with a suitable lymphoid tumor cell

Transfection with tumor derived DNA

poor recognition of immunoglobulin, Ig constant regions

presence of HAMA response

All of these

absence of human immune response against murine proteins (HAMA) response

immortalizes the donor Bcells

All of these

facilitates the proliferation of antigen specific B cells

gives much higher hybridization frequencies

dendritic cells

plasma cells

T cells

macrophages

none of these

both (a) and (b)

as ascites in peritoneal cavity of mice

in tissue culture