The role of Asp 102 and His 57 during trypsin catalysis is to function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain TRUE ANSWER : ? YOUR ANSWER : ?
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A, B, C, and D will all still be produced A and B will still be produced, but not C or D A, B, and C will still be produced, but not D A will still be produced, but not B, C, or D TRUE ANSWER : ? YOUR ANSWER : ?
The cleavage specificity of trypsin and chymotrypsin depend in part on the absence of water in the active site size, shape, and charge of the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket TRUE ANSWER : ? YOUR ANSWER : ?
What is the specificity of the Clostripain protease? None of these It cleave after His residues It cleave after Arg residues It cleave after Lys residues TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following statements about enzymes or their function is true? All of these Enzymes are proteins whose three-dimensional form is key to their function Enzymes speed up reactions by lowering activation energy Enzymes do not alter the overall change in free energy for a reaction TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following (s) is/are serine proteases? Chymotrypsin all of these Elastase Trypsin TRUE ANSWER : ? YOUR ANSWER : ?
How is the enzyme COX-1 important in human health? It helps to transport carbon dioxide in the blood It is a chemical derivative of aspirin It is critical for the biosynthesis of DNA It catalyzes the production of hormones that maintain the stomach lining TRUE ANSWER : ? YOUR ANSWER : ?
Which of the common features are shared between serine and aspartate proteases? Both require water to complete the catalytic cycle All of these Both show specificity for certain amino acid sequences Both use a base to activate the nucleophile TRUE ANSWER : ? YOUR ANSWER : ?
Enzyme-driven metabolic pathways can be made more efficient by grouping enzymes into free-floating, multienzyme complexes concentrating enzymes within specific cellular compartments fixing enzymes into membranes so that they are adjacent to each other All of these TRUE ANSWER : ? YOUR ANSWER : ?
The E.coli pyruvic acid dehydrogenase complex is reported to retard the reduction of pyruvic acid to acetyl Co A and CO2 decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 TRUE ANSWER : ? YOUR ANSWER : ?