The cleavage specificity of trypsin and chymotrypsin depend in part on the presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following statements about enzymes or their function is true? Enzymes do not alter the overall change in free energy for a reaction Enzymes are proteins whose three-dimensional form is key to their function Enzymes speed up reactions by lowering activation energy All of these TRUE ANSWER : ? YOUR ANSWER : ?
Which of the common features are shared between serine and aspartate proteases? Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile TRUE ANSWER : ? YOUR ANSWER : ?
How is the enzyme COX-1 important in human health? It helps to transport carbon dioxide in the blood It catalyzes the production of hormones that maintain the stomach lining It is critical for the biosynthesis of DNA It is a chemical derivative of aspirin TRUE ANSWER : ? YOUR ANSWER : ?
Common feature in all serine proteases is a hydrophilic specificity pocket single reactive serine residue hydrophobic specificity pocket cluster of reactive serine residues TRUE ANSWER : ? YOUR ANSWER : ?
Enzyme-driven metabolic pathways can be made more efficient by concentrating enzymes within specific cellular compartments fixing enzymes into membranes so that they are adjacent to each other grouping enzymes into free-floating, multienzyme complexes All of these TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following (s) is/are serine proteases? Elastase Trypsin Chymotrypsin all of these TRUE ANSWER : ? YOUR ANSWER : ?
Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of a protein designated A two proteins designated A and B a protein A and one-subunit a a protein designated B TRUE ANSWER : ? YOUR ANSWER : ?
Before they can react, many molecules need to be destabilized. This state is typically achieved through changing the reaction from a biosynthetic to a catabolic pathway changing the three-dimensional shape of the molecule oxidizing the molecules by removing electrons the input of a small amount of activation energy TRUE ANSWER : ? YOUR ANSWER : ?
The nucleophile in serine proteases is Asparagine water Serine both (a) and (b) TRUE ANSWER : ? YOUR ANSWER : ?