DNA STRUCTURE AND REPLICATION QUIZ

dispersive replication

semi-conservative replication

Cri du Chat

conservative replication

are removed by helicase + ATP

result in Okazaki fragments on leading strand

are removed by Pol I

are joined together by DNA ligase

Polymerase II

Polymerase I

Polymerase III

all of these

solenoid

halonoid

kinoplast

none of these

break a phosphodiester bond in DNA strand

interact the double helix closely

None of these

unwind the double helix

5' → 3' endonuclease activity

5' → 3' exonuclease activity

partially 5' → 3' endonuclease activity

partially 5' → 3' exonuclease activity

but with a polynucleotide primer labeled with a fluorescent dye

but with an oligonucleotide primer labeled with a fluorescent dye

with no primer

either (b) or (c)

AZT (zidovudine) is too expensive to be taken in effective doses

It has low affinity for the correct dNTP's

The RNase H domain of p66 causes error prone synthesis

It lacks a proofreading exonuclease

performs the same function as helicase in eukaryotes

adds positive supercoils to chromosomal DNA

can be inhibited with antibiotics

is required only at the oriC site

S, G2 and M phases

G1, G2 and M phases

G2 and M phases

G1,S, G2 and M phases