DNA STRUCTURE AND REPLICATION QUIZ

The chromosomal DNA complexes with

three types of histone as H1, H2A and H4

four types of histone as H1, H2A, H3 and H4

two types of histone as H1 and H4

five types of histone as H1, H2A, H2B, H3 and H4

TRUE ANSWER : ?
YOUR ANSWER : ?

The 5' and 3' numbers are related to the

length of the DNA strand

carbon number in sugar

the number of phosphates

the base pair rule

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30 nm wide helix with five or six nucleosomes per helix is known as

solenoid

halonoid

none of these

kinoplast

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YOUR ANSWER : ?

The packing ratio of nucleosomes is about

6

9

8

7

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Taylor, Woods and Hughes labeled Vicia DNA by allowing new DNA synthesis in the presence of radioactive thymine. After DNA replication (S phase of the cell cycle), it was observed that

neither chromatid was labeled

only one chromatid of a chromosome was labeled

both chromatids of a chromosome were labeled

both (a) and (b)

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Which histone(s) are associated with the linker DNA of a nucleosome?

Histone H3

Histone H1

Histone H4

Histones H2A and H2B

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What is the main damaging effect of UV radiation on DNA?

Dehydration

Formation of thymine dimers

Single strand break

Depurination

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The B-DNA structure found in solution is a

left-handed double helix of antiparallel chains (10 bp/turn)

right-handed double helix of antiparallel chains (∼10 bp/turn)

left-handed zig-zag helix of antiparallel chains (10 bp/turn)

right-handed double helix of parallel chains (∼10 bp/turn)

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The size of a linear DNA fragment in a gel can be estimated by

fluorescence in UV light

the time it takes the gel to run

the sedimentation coefficient

comparison with a molecular weight standard such as Hind III digested phage lambda

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The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by

shortening of the double stranded replicated portion

using RNA as a template

None of these

using enzyme called telomerase

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