DNA SEQUENCING, MUTATION AND REPAIR QUIZ

Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?

New strands are methylated while old strands are not

New strands do not contain cytosine bases

Old strands are methylated while new strands are not

New strands are lower in molecular size

TRUE ANSWER : ?
YOUR ANSWER : ?

Frame shift mutation may occur as a result of

deamination of cytosine to uracil

conversion of guanine to xanthine

None of these

formation of a thymine-dimer

TRUE ANSWER : ?
YOUR ANSWER : ?

What was the first eukaryotic chromosome to be sequenced?

Yeast chromosome III

Arabidopsis chromosome IV

Yeast chromosome XI

None of these

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of these mechanisms for thymine dimers repair lead to mutations?

Excision repair

Never leads to mutation

SOS repair

Photoreactivation

TRUE ANSWER : ?
YOUR ANSWER : ?

A nonsense mutation may result into

modification of mRNA

a large deletion within the reading frame of a gene

an abnormal elongation of a polypeptide

a premature termination of the synthesis of a polypeptide

TRUE ANSWER : ?
YOUR ANSWER : ?

Genetic variations are

temporary

influenced by the environment

stable

not heritable

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following bacterial genome was sequenced first?

S. thermophilus

H. influenzae

S. pneumoniae

E. coli

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following mutations arise without exposure to external agents?

None of these

Induced mutations

Spontaneous mutations

Analogous mutations

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following(s) is/are steps in excision repair mechanisms?

Incision

Excision

Ligation

All of these

TRUE ANSWER : ?
YOUR ANSWER : ?

Differentiation of four different bases in automated sequencing systems is that each base has

unique antibody bound to it

distinctive fluorescent tag

cytosine at start

different radioactive tag

TRUE ANSWER : ?
YOUR ANSWER : ?