DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Leu or Ileu

Ser or Thr

Tyr or Phe

His or Pro

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X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of B cells to provide co-stimulation for Th2 activation

failure of Th2 cells to provide co-stimulation for B cell proliferation

failure of Th2 cells to provide co-stimulation for B cell isotype switching

activation of B cells by T-independent antigens

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The HIV virus infects primarily

cells in the immune system

liver cells

brain cells

red blood cells

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Which of the Rous sarcoma virus has a homologous cellular protein?

v-ha-src

c-src

v-ha-ras

v-src

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A selective IgA deficiency would be expected to result in problems with

mucosal pathogens

bacterial infections

pathogens which can survive inside macrophages

infections following dental work due to bacteria entering the bloodstream

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Specific translocations are associated with

breast cancer

some leukemias

pancreatic cancer

colon cancer

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If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

alternative complement activation.

CD8 T cell-mediated cytotoxicity

macrophage activation to vesicular pathogens

IgG synthesis

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Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

CTL killing of viruses

macrophage intracellular killing of bacteria

dendritic cell activation to become a mature APC

infected cell processing of virus peptides

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Retinoblastoma is due to a mutation in a

kinase

tumor supressor

cyclin

viral gene

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The chemical, typically released by the body in an allergic response is

perforins

allergens

histamine

antihistamines

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