DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

Combined cellular and humoral immune deficiencies result from lack of all of the following except

a thymus

HIV infection of CD4+ T cells

class II MHC

transporter of antigen peptides (TAP)

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The primary reason for AIDS, a deadly disease is that it

destroys key components of the body's internal defense system

is caused by a virus

is caused by a bacterium

causes a breakdown of the body's inflammatory response

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To treat HIV infections using drugs, the major problem is that

the virus particles with altered (mutant) proteases arise

the drugs interfere with normal digestion

the drugs are rapidly degraded

the drugs that are good inhibitors cannot by synthesized

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

in utero (before birth)

at 0-3 months of age

at 3-12 months of age

at 12-24 months of age

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An example of an immunodeficiency disorder is

thyroiditis

AIDS

rheumatic fever

systemic lupus erythematosus

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The chemical, typically released by the body in an allergic response is

histamine

antihistamines

perforins

allergens

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Specific translocations are associated with

colon cancer

some leukemias

breast cancer

pancreatic cancer

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Which of the Rous sarcoma virus has a homologous cellular protein?

v-src

v-ha-src

c-src

v-ha-ras

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A selective IgA deficiency would be expected to result in problems with

bacterial infections

pathogens which can survive inside macrophages

mucosal pathogens

infections following dental work due to bacteria entering the bloodstream

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DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

recombinant mouse for CD3

knock-out mouse for a thymus

knock-out mouse for RAG-1 and RAG-2

nude mouse

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