DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

An example of an immunodeficiency disorder is

thyroiditis

systemic lupus erythematosus

rheumatic fever

AIDS

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Which of the Rous sarcoma virus has a homologous cellular protein?

v-src

v-ha-ras

v-ha-src

c-src

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DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

nude mouse

recombinant mouse for CD3

knock-out mouse for a thymus

knock-out mouse for RAG-1 and RAG-2

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Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

dendritic cell activation to become a mature APC

macrophage intracellular killing of bacteria

CTL killing of viruses

infected cell processing of virus peptides

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An autoimmune disease is

Mumps

Lupus

Measles

AIDS

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A selective IgA deficiency would be expected to result in problems with

bacterial infections

mucosal pathogens

pathogens which can survive inside macrophages

infections following dental work due to bacteria entering the bloodstream

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Combined cellular and humoral immune deficiencies result from lack of all of the following except

a thymus

transporter of antigen peptides (TAP)

class II MHC

HIV infection of CD4+ T cells

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The primary reason for AIDS, a deadly disease is that it

causes a breakdown of the body's inflammatory response

is caused by a bacterium

destroys key components of the body's internal defense system

is caused by a virus

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The chemical, typically released by the body in an allergic response is

allergens

perforins

histamine

antihistamines

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X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of Th2 cells to provide co-stimulation for B cell isotype switching

failure of B cells to provide co-stimulation for Th2 activation

failure of Th2 cells to provide co-stimulation for B cell proliferation

activation of B cells by T-independent antigens

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