DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

To treat HIV infections using drugs, the major problem is that

the drugs interfere with normal digestion

the drugs are rapidly degraded

the drugs that are good inhibitors cannot by synthesized

the virus particles with altered (mutant) proteases arise

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Specific translocations are associated with

colon cancer

pancreatic cancer

some leukemias

breast cancer

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The chemical, typically released by the body in an allergic response is

allergens

antihistamines

perforins

histamine

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 0-3 months of age

at 3-12 months of age

in utero (before birth)

at 12-24 months of age

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X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

activation of B cells by T-independent antigens

failure of Th2 cells to provide co-stimulation for B cell proliferation

failure of B cells to provide co-stimulation for Th2 activation

failure of Th2 cells to provide co-stimulation for B cell isotype switching

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Retinoblastoma is due to a mutation in a

cyclin

viral gene

tumor supressor

kinase

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An example of an immunodeficiency disorder is

AIDS

rheumatic fever

thyroiditis

systemic lupus erythematosus

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A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Ser or Thr

Tyr or Phe

Leu or Ileu

His or Pro

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A selective IgA deficiency would be expected to result in problems with

pathogens which can survive inside macrophages

mucosal pathogens

infections following dental work due to bacteria entering the bloodstream

bacterial infections

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DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

knock-out mouse for RAG-1 and RAG-2

recombinant mouse for CD3

knock-out mouse for a thymus

nude mouse

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