DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

Specific translocations are associated with

pancreatic cancer

some leukemias

breast cancer

colon cancer

TRUE ANSWER : ?
YOUR ANSWER : ?

Retinoblastoma is due to a mutation in a

kinase

tumor supressor

viral gene

cyclin

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the Rous sarcoma virus has a homologous cellular protein?

v-ha-ras

v-ha-src

v-src

c-src

TRUE ANSWER : ?
YOUR ANSWER : ?

If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

CD8 T cell-mediated cytotoxicity

macrophage activation to vesicular pathogens

alternative complement activation.

IgG synthesis

TRUE ANSWER : ?
YOUR ANSWER : ?

Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

macrophage intracellular killing of bacteria

CTL killing of viruses

dendritic cell activation to become a mature APC

infected cell processing of virus peptides

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Bone marrow given to an infant with SCID must

contain mature T cells that can begin making immune responses immediately

come from a donor that shares some MHC alleles with the recipient

come from one of the child's parents

be irradiated to eliminate GVHD

TRUE ANSWER : ?
YOUR ANSWER : ?

A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

His or Pro

Tyr or Phe

Ser or Thr

Leu or Ileu

TRUE ANSWER : ?
YOUR ANSWER : ?

An example of an immunodeficiency disorder is

systemic lupus erythematosus

rheumatic fever

thyroiditis

AIDS

TRUE ANSWER : ?
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To treat HIV infections using drugs, the major problem is that

the drugs that are good inhibitors cannot by synthesized

the drugs are rapidly degraded

the virus particles with altered (mutant) proteases arise

the drugs interfere with normal digestion

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Difficulties with somatic gene therapy arise from all of the following except

limited life span of more mature hematopoietic cells

inserting a gene so that it will function properly

transducing genetic material into stem cells

GVHD caused by mature T cells in the transplanted cells

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