If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced alternative complement activation. IgG synthesis CD8 T cell-mediated cytotoxicity macrophage activation to vesicular pathogens TRUE ANSWER : ? YOUR ANSWER : ?
Specific translocations are associated with some leukemias breast cancer pancreatic cancer colon cancer TRUE ANSWER : ? YOUR ANSWER : ?
To treat HIV infections using drugs, the major problem is that the drugs are rapidly degraded the drugs that are good inhibitors cannot by synthesized the virus particles with altered (mutant) proteases arise the drugs interfere with normal digestion TRUE ANSWER : ? YOUR ANSWER : ?
A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind Tyr or Phe Ser or Thr Leu or Ileu His or Pro TRUE ANSWER : ? YOUR ANSWER : ?
DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a knock-out mouse for RAG-1 and RAG-2 recombinant mouse for CD3 nude mouse knock-out mouse for a thymus TRUE ANSWER : ? YOUR ANSWER : ?
Difficulties with somatic gene therapy arise from all of the following except GVHD caused by mature T cells in the transplanted cells limited life span of more mature hematopoietic cells transducing genetic material into stem cells inserting a gene so that it will function properly TRUE ANSWER : ? YOUR ANSWER : ?
Retinoblastoma is due to a mutation in a cyclin viral gene tumor supressor kinase TRUE ANSWER : ? YOUR ANSWER : ?
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with infected cell processing of virus peptides macrophage intracellular killing of bacteria dendritic cell activation to become a mature APC CTL killing of viruses TRUE ANSWER : ? YOUR ANSWER : ?
Which of the Rous sarcoma virus has a homologous cellular protein? v-ha-src v-ha-ras c-src v-src TRUE ANSWER : ? YOUR ANSWER : ?