DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

Combined cellular and humoral immune deficiencies result from lack of all of the following except

class II MHC

a thymus

HIV infection of CD4+ T cells

transporter of antigen peptides (TAP)

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A selective IgA deficiency would be expected to result in problems with

pathogens which can survive inside macrophages

infections following dental work due to bacteria entering the bloodstream

mucosal pathogens

bacterial infections

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The primary reason for AIDS, a deadly disease is that it

is caused by a virus

is caused by a bacterium

destroys key components of the body's internal defense system

causes a breakdown of the body's inflammatory response

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 0-3 months of age

at 3-12 months of age

at 12-24 months of age

in utero (before birth)

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The chemical, typically released by the body in an allergic response is

antihistamines

allergens

histamine

perforins

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To treat HIV infections using drugs, the major problem is that

the drugs interfere with normal digestion

the drugs are rapidly degraded

the virus particles with altered (mutant) proteases arise

the drugs that are good inhibitors cannot by synthesized

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Which of the Rous sarcoma virus has a homologous cellular protein?

v-ha-ras

v-ha-src

v-src

c-src

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Specific translocations are associated with

breast cancer

pancreatic cancer

colon cancer

some leukemias

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A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Tyr or Phe

Ser or Thr

Leu or Ileu

His or Pro

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Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

CTL killing of viruses

infected cell processing of virus peptides

macrophage intracellular killing of bacteria

dendritic cell activation to become a mature APC

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