DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

An example of an immunodeficiency disorder is

AIDS

systemic lupus erythematosus

thyroiditis

rheumatic fever

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Bone marrow given to an infant with SCID must

contain mature T cells that can begin making immune responses immediately

come from a donor that shares some MHC alleles with the recipient

be irradiated to eliminate GVHD

come from one of the child's parents

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To treat HIV infections using drugs, the major problem is that

the drugs are rapidly degraded

the drugs interfere with normal digestion

the virus particles with altered (mutant) proteases arise

the drugs that are good inhibitors cannot by synthesized

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X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of Th2 cells to provide co-stimulation for B cell proliferation

activation of B cells by T-independent antigens

failure of B cells to provide co-stimulation for Th2 activation

failure of Th2 cells to provide co-stimulation for B cell isotype switching

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Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

dendritic cell activation to become a mature APC

CTL killing of viruses

macrophage intracellular killing of bacteria

infected cell processing of virus peptides

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A selective IgA deficiency would be expected to result in problems with

infections following dental work due to bacteria entering the bloodstream

mucosal pathogens

pathogens which can survive inside macrophages

bacterial infections

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Specific translocations are associated with

some leukemias

pancreatic cancer

colon cancer

breast cancer

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An autoimmune disease is

Mumps

Measles

AIDS

Lupus

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The primary reason for AIDS, a deadly disease is that it

is caused by a bacterium

is caused by a virus

causes a breakdown of the body's inflammatory response

destroys key components of the body's internal defense system

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The HIV virus infects primarily

brain cells

cells in the immune system

liver cells

red blood cells

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