DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

infected cell processing of virus peptides

CTL killing of viruses

macrophage intracellular killing of bacteria

dendritic cell activation to become a mature APC

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Bone marrow given to an infant with SCID must

come from a donor that shares some MHC alleles with the recipient

be irradiated to eliminate GVHD

come from one of the child's parents

contain mature T cells that can begin making immune responses immediately

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Specific translocations are associated with

breast cancer

colon cancer

pancreatic cancer

some leukemias

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The primary reason for AIDS, a deadly disease is that it

is caused by a virus

is caused by a bacterium

causes a breakdown of the body's inflammatory response

destroys key components of the body's internal defense system

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The chemical, typically released by the body in an allergic response is

antihistamines

histamine

perforins

allergens

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To treat HIV infections using drugs, the major problem is that

the virus particles with altered (mutant) proteases arise

the drugs interfere with normal digestion

the drugs are rapidly degraded

the drugs that are good inhibitors cannot by synthesized

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The HIV virus infects primarily

brain cells

liver cells

cells in the immune system

red blood cells

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Difficulties with somatic gene therapy arise from all of the following except

GVHD caused by mature T cells in the transplanted cells

transducing genetic material into stem cells

limited life span of more mature hematopoietic cells

inserting a gene so that it will function properly

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Which of the Rous sarcoma virus has a homologous cellular protein?

c-src

v-ha-ras

v-ha-src

v-src

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Combined cellular and humoral immune deficiencies result from lack of all of the following except

class II MHC

transporter of antigen peptides (TAP)

HIV infection of CD4+ T cells

a thymus

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