DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of Th2 cells to provide co-stimulation for B cell proliferation

failure of B cells to provide co-stimulation for Th2 activation

activation of B cells by T-independent antigens

failure of Th2 cells to provide co-stimulation for B cell isotype switching

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A selective IgA deficiency would be expected to result in problems with

mucosal pathogens

infections following dental work due to bacteria entering the bloodstream

bacterial infections

pathogens which can survive inside macrophages

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The chemical, typically released by the body in an allergic response is

antihistamines

histamine

perforins

allergens

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To treat HIV infections using drugs, the major problem is that

the drugs are rapidly degraded

the drugs that are good inhibitors cannot by synthesized

the drugs interfere with normal digestion

the virus particles with altered (mutant) proteases arise

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 0-3 months of age

at 3-12 months of age

in utero (before birth)

at 12-24 months of age

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The HIV virus infects primarily

brain cells

cells in the immune system

red blood cells

liver cells

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An autoimmune disease is

Measles

Mumps

Lupus

AIDS

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Retinoblastoma is due to a mutation in a

tumor supressor

cyclin

kinase

viral gene

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The primary reason for AIDS, a deadly disease is that it

is caused by a bacterium

is caused by a virus

causes a breakdown of the body's inflammatory response

destroys key components of the body's internal defense system

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If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

IgG synthesis

alternative complement activation.

CD8 T cell-mediated cytotoxicity

macrophage activation to vesicular pathogens

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