DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

An example of an immunodeficiency disorder is

thyroiditis

systemic lupus erythematosus

AIDS

rheumatic fever

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Bone marrow given to an infant with SCID must

contain mature T cells that can begin making immune responses immediately

come from a donor that shares some MHC alleles with the recipient

be irradiated to eliminate GVHD

come from one of the child's parents

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 0-3 months of age

at 3-12 months of age

at 12-24 months of age

in utero (before birth)

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If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

CD8 T cell-mediated cytotoxicity

IgG synthesis

alternative complement activation.

macrophage activation to vesicular pathogens

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To treat HIV infections using drugs, the major problem is that

the drugs are rapidly degraded

the drugs interfere with normal digestion

the virus particles with altered (mutant) proteases arise

the drugs that are good inhibitors cannot by synthesized

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The primary reason for AIDS, a deadly disease is that it

is caused by a bacterium

is caused by a virus

causes a breakdown of the body's inflammatory response

destroys key components of the body's internal defense system

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Retinoblastoma is due to a mutation in a

cyclin

tumor supressor

kinase

viral gene

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The chemical, typically released by the body in an allergic response is

perforins

allergens

antihistamines

histamine

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Specific translocations are associated with

pancreatic cancer

colon cancer

some leukemias

breast cancer

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Difficulties with somatic gene therapy arise from all of the following except

GVHD caused by mature T cells in the transplanted cells

inserting a gene so that it will function properly

transducing genetic material into stem cells

limited life span of more mature hematopoietic cells

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