DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

His or Pro

Ser or Thr

Leu or Ileu

Tyr or Phe

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Combined cellular and humoral immune deficiencies result from lack of all of the following except

class II MHC

transporter of antigen peptides (TAP)

a thymus

HIV infection of CD4+ T cells

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

in utero (before birth)

at 0-3 months of age

at 3-12 months of age

at 12-24 months of age

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The primary reason for AIDS, a deadly disease is that it

is caused by a virus

is caused by a bacterium

causes a breakdown of the body's inflammatory response

destroys key components of the body's internal defense system

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If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

macrophage activation to vesicular pathogens

CD8 T cell-mediated cytotoxicity

alternative complement activation.

IgG synthesis

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An autoimmune disease is

Lupus

AIDS

Mumps

Measles

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The HIV virus infects primarily

red blood cells

cells in the immune system

brain cells

liver cells

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Specific translocations are associated with

breast cancer

some leukemias

colon cancer

pancreatic cancer

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X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of Th2 cells to provide co-stimulation for B cell isotype switching

failure of Th2 cells to provide co-stimulation for B cell proliferation

failure of B cells to provide co-stimulation for Th2 activation

activation of B cells by T-independent antigens

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DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

knock-out mouse for RAG-1 and RAG-2

knock-out mouse for a thymus

nude mouse

recombinant mouse for CD3

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