DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

Specific translocations are associated with

some leukemias

breast cancer

pancreatic cancer

colon cancer

TRUE ANSWER : ?
YOUR ANSWER : ?

Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

CTL killing of viruses

infected cell processing of virus peptides

macrophage intracellular killing of bacteria

dendritic cell activation to become a mature APC

TRUE ANSWER : ?
YOUR ANSWER : ?

Combined cellular and humoral immune deficiencies result from lack of all of the following except

transporter of antigen peptides (TAP)

a thymus

class II MHC

HIV infection of CD4+ T cells

TRUE ANSWER : ?
YOUR ANSWER : ?

Retinoblastoma is due to a mutation in a

tumor supressor

cyclin

viral gene

kinase

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the Rous sarcoma virus has a homologous cellular protein?

v-ha-src

v-src

v-ha-ras

c-src

TRUE ANSWER : ?
YOUR ANSWER : ?

The HIV virus infects primarily

cells in the immune system

liver cells

brain cells

red blood cells

TRUE ANSWER : ?
YOUR ANSWER : ?

To treat HIV infections using drugs, the major problem is that

the drugs interfere with normal digestion

the drugs are rapidly degraded

the drugs that are good inhibitors cannot by synthesized

the virus particles with altered (mutant) proteases arise

TRUE ANSWER : ?
YOUR ANSWER : ?

Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 3-12 months of age

in utero (before birth)

at 12-24 months of age

at 0-3 months of age

TRUE ANSWER : ?
YOUR ANSWER : ?

Difficulties with somatic gene therapy arise from all of the following except

inserting a gene so that it will function properly

limited life span of more mature hematopoietic cells

GVHD caused by mature T cells in the transplanted cells

transducing genetic material into stem cells

TRUE ANSWER : ?
YOUR ANSWER : ?

X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of Th2 cells to provide co-stimulation for B cell isotype switching

failure of B cells to provide co-stimulation for Th2 activation

activation of B cells by T-independent antigens

failure of Th2 cells to provide co-stimulation for B cell proliferation

TRUE ANSWER : ?
YOUR ANSWER : ?