DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

An example of an immunodeficiency disorder is

rheumatic fever

thyroiditis

AIDS

systemic lupus erythematosus

TRUE ANSWER : ?
YOUR ANSWER : ?

Retinoblastoma is due to a mutation in a

viral gene

cyclin

kinase

tumor supressor

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the Rous sarcoma virus has a homologous cellular protein?

v-ha-src

v-ha-ras

c-src

v-src

TRUE ANSWER : ?
YOUR ANSWER : ?

X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

activation of B cells by T-independent antigens

failure of B cells to provide co-stimulation for Th2 activation

failure of Th2 cells to provide co-stimulation for B cell isotype switching

failure of Th2 cells to provide co-stimulation for B cell proliferation

TRUE ANSWER : ?
YOUR ANSWER : ?

Specific translocations are associated with

pancreatic cancer

colon cancer

some leukemias

breast cancer

TRUE ANSWER : ?
YOUR ANSWER : ?

Infants are most susceptible to bacterial infection due to low circulating levels of IgG

at 0-3 months of age

at 12-24 months of age

at 3-12 months of age

in utero (before birth)

TRUE ANSWER : ?
YOUR ANSWER : ?

Bone marrow given to an infant with SCID must

come from one of the child's parents

contain mature T cells that can begin making immune responses immediately

come from a donor that shares some MHC alleles with the recipient

be irradiated to eliminate GVHD

TRUE ANSWER : ?
YOUR ANSWER : ?

A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Leu or Ileu

Ser or Thr

Tyr or Phe

His or Pro

TRUE ANSWER : ?
YOUR ANSWER : ?

Difficulties with somatic gene therapy arise from all of the following except

transducing genetic material into stem cells

GVHD caused by mature T cells in the transplanted cells

inserting a gene so that it will function properly

limited life span of more mature hematopoietic cells

TRUE ANSWER : ?
YOUR ANSWER : ?

DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

recombinant mouse for CD3

knock-out mouse for a thymus

knock-out mouse for RAG-1 and RAG-2

nude mouse

TRUE ANSWER : ?
YOUR ANSWER : ?