ANTIMICROBIAL CHEMOTHERAPEUTIC AGENTS QUIZ

both (a) and (b)

trimethoprim

none of these

sulphonamides

Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis

Interfere with normal nucleic acid synthesis

Interfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic membrane as well as the function of several membrane-bound enzymes like those involved in nutrient transport and chitin synthesis

all of these

cell wall synthesis

DNA function

cell membrane function

protein synthesis

large ring structures

any of these

β-lactam - thiazolidine ring

small ring structures

Peptide bond formation

All of these

mRNA translocation

Aminoacyl-tRNA binding

kills all bacteria

kills numerous types of microbes

kills all microorganisms

kills both Gram positive and Gram negative bacteria

Nisin

Tylosin

Pimaricin

β-lactam antibiotic

Methicillin

Oxacillin

Nafcillin

Carbenicillin

Cell membrane function

DNA function

Cell wall synthesis

Protein synthesis

are inactivated by β-lactamase

must be transported into the cytoplasm in order to act

bind to and inactivate a bacterial protein

inhibit the cross-linking of peptidoglycan