ANTIMICROBIAL CHEMOTHERAPEUTIC AGENTS QUIZ

A broad-spectrum antibiotic such as chloramphenicol is one that

kills all microorganisms

kills numerous types of microbes

kills all bacteria

kills both Gram positive and Gram negative bacteria

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following may cause resistance to penicillin?

Production of β-lactamases by bacteria

Alteration or lack of penicillin-binding proteins

Impermeability of cell envelope

All of these

TRUE ANSWER : ?
YOUR ANSWER : ?

Vancomycin inhibits peptidoglycan synthesis by binding

D-alanyl - D-alanine

alanine racemase

amidase

D-alanyl - D-alanine synthetase

TRUE ANSWER : ?
YOUR ANSWER : ?

The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

tetracycline

vancomycin

metronidazole

gentamicin

TRUE ANSWER : ?
YOUR ANSWER : ?

The susceptibility of a microorganism to antibiotics and other chemotherapeutic agents can be determined by using

tube dilution technique

none of these

paper disk plate

both (a) and (b)

TRUE ANSWER : ?
YOUR ANSWER : ?

Polyene antibiotics are

any of these

small ring structures

β-lactam - thiazolidine ring

large ring structures

TRUE ANSWER : ?
YOUR ANSWER : ?

The mode of action of polymyxin is to

inhibit folic acid synthesis

inhibit protein synthesis

inhibit DNA synthesis

injury to the plasma membrane

TRUE ANSWER : ?
YOUR ANSWER : ?

A parenteral route of drug administration refers to

nonoral

oral

intramuscularly

intravenously

TRUE ANSWER : ?
YOUR ANSWER : ?

The larger the __________ , the better the chemotherapeutic agent.

spectrum

therapeutic index

selective toxicity

therapeutic dose

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following is not β-lactamase-resistant penicillin?

Oxacillin

Nafcillin

Methicillin

Carbenicillin

TRUE ANSWER : ?
YOUR ANSWER : ?

↑