ANTIMICROBIAL CHEMOTHERAPEUTIC AGENTS QUIZ

The antibiotics not clinically useful for Pseudomonas aeruginosa infection is

trimethoprim-sulphamethoxazole

piperacillin

aminoglycosides

ceftazidime

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following methods would be most appropriate for sterilizing an antibiotic solution?

Dry heat sterilization

Autoclaving

Microfiltration

Desiccation

TRUE ANSWER : ?
YOUR ANSWER : ?

The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

tetracycline

gentamicin

metronidazole

vancomycin

TRUE ANSWER : ?
YOUR ANSWER : ?

The penicillin resistant to β-lactamases is

penicillin-G

carbenicillin

ampicillin

closacillin

TRUE ANSWER : ?
YOUR ANSWER : ?

Which antibiotic has a beta-lactam ring?

Streptomycin

Cephalosporin

Tetracycline

Penicillin

TRUE ANSWER : ?
YOUR ANSWER : ?

Both penicillin and fluoroquinolones

must be transported into the cytoplasm in order to act

inhibit the cross-linking of peptidoglycan

bind to and inactivate a bacterial protein

are inactivated by β-lactamase

TRUE ANSWER : ?
YOUR ANSWER : ?

Polyene antibiotics are

β-lactam - thiazolidine ring

large ring structures

any of these

small ring structures

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following protein synthesis mechanisms may be affected by particular drugs?

Aminoacyl-tRNA binding

Peptide bond formation

mRNA translocation

All of these

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following may cause resistance to penicillin?

Alteration or lack of penicillin-binding proteins

Impermeability of cell envelope

Production of β-lactamases by bacteria

All of these

TRUE ANSWER : ?
YOUR ANSWER : ?

The larger the __________ , the better the chemotherapeutic agent.

therapeutic dose

selective toxicity

therapeutic index

spectrum

TRUE ANSWER : ?
YOUR ANSWER : ?

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