ANTIMICROBIAL CHEMOTHERAPEUTIC AGENTS QUIZ

Amphotericin B and polymyxin interfere with

cell membrane function

protein synthesis

DNA function

cell wall synthesis

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YOUR ANSWER : ?

The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

metronidazole

tetracycline

gentamicin

vancomycin

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YOUR ANSWER : ?

Which of the following antibiotics can't be used for treatment of infections with β-lactamase-producing Staphylococcus aureus?

Piperacillin

Vancomycin

Cephalothin

Ampicillin/sulbactam

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YOUR ANSWER : ?

Fluoroquinolones are antibiotics which inhibit

DNA polymerase

Cross-linking of peptidoglycan

RNA polymerase

DNA gyrase

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Which of the following is a drug that interferes with the process of DNA production in the virus that causes genital herpes?

Vancomycin

Amantadine

Erythromycin

Acyclovir

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Which of the following protein synthesis mechanisms may be affected by particular drugs?

All of these

Peptide bond formation

Aminoacyl-tRNA binding

mRNA translocation

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Cycloserine inhibits

Both (a) and (b)

amidase

D-alanyl - D-alanine synthetase

alanine racemase

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The larger the __________ , the better the chemotherapeutic agent.

therapeutic dose

selective toxicity

spectrum

therapeutic index

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YOUR ANSWER : ?

By which of the following means antifungal chemotherapeutic agents may affect fungi?

Interfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic membrane as well as the function of several membrane-bound enzymes like those involved in nutrient transport and chitin synthesis

Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis

Interfere with normal nucleic acid synthesis

all of these

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Which is not an amino acid and peptide antibiotic?

Actinomycin

Bacitracin

Penicillin

Tetranactin

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