ANTIBODY QUIZ | EXAMIANS

J chain is present in

IgA

IgM

Both (a) and (b)

IgE

TRUE ANSWER : ?
YOUR ANSWER : ?

The secretary component of sIgA is

formed by cleavage of an epithelial cell receptor used to transport the dimeric IgA across the epithelial cell

added to dimeric IgA by the M cell

made by T cells

made by plasma cells that secrete dimeric IgA

TRUE ANSWER : ?
YOUR ANSWER : ?

Which is not a function of IgG?

Involved in opsonization

First antibody type produced against an antigen during the primary antibody response

Activates or fixes complement

Major antibody in serum

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following mediates Type I hypersensitivity reaction?

IgD

IgM

IgE

IgG

TRUE ANSWER : ?
YOUR ANSWER : ?

Simulation of which of the following will lead to appearance of first antibody to appear following stimulation by an antigen?

IgG

IgM

IgE

IgA

TRUE ANSWER : ?
YOUR ANSWER : ?

The class of immunoglobulin, most abundant in body is

IgD

IgG

IgM

IgE

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following (s) is/are function (s) of Fc fragment of IgG?

It determines catabolic rate

All of these

It binds complement

It is related to passage of IgG across the placental barrier

TRUE ANSWER : ?
YOUR ANSWER : ?

Antigen binding sites of an immunoglobulin are located in

Fc region of the antibody

light chain alone

Fab regions of the antibody

heavy chain alone

TRUE ANSWER : ?
YOUR ANSWER : ?

The class of immunoglobulins which can cross the placenta is

IgG

IgM

IgA

IgD

TRUE ANSWER : ?
YOUR ANSWER : ?

Self reactive antibodies are not found in significant concentration in normal serum because

self reactive B cells are killed by CD8 T cells

self reactive B cells switch to IgA which is all secreted and not present in serum

B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

it is impossible to generate a self-reactive antibody

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