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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Novobiocin can be used against

gram +ve Staphylococci
all of these
gram -ve Meningococci & Gonococci
Haemophilus

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Antimicrobial Chemotherapeutic Agents
Quinolones are

antimetabolites
penicillin derivatives
bacteriostatic
broad-spectrum

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Antimicrobial Chemotherapeutic Agents
The antibiotics not clinically useful for Pseudomonas aeruginosa infection is

ceftazidime
aminoglycosides
trimethoprim-sulphamethoxazole
piperacillin

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Antimicrobial Chemotherapeutic Agents
Chelate forming peptide antibiotic are/is

sideromycins
vancomycin
bleomycins
both (a) and (b)

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Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

injury to the plasma membrane
inhibit protein synthesis
inhibit folic acid synthesis
inhibit DNA synthesis

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

bind to and inactivate a bacterial protein
are inactivated by β-lactamase
must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan

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