Translation and Regulation
Negative regulation of protein synthesis is accomplished by

the binding of a repressor to the DNA
the binding of a repressor to the RNA polymerase
allosteric inhibition
the binding of RNA polymerase to the promoter

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Translation and Regulation
The role of molecular chaperones is to

facilitate binding of RNA polymerase to DNA
aid a newly synthesized polypeptide in folding to its proper shape
degrade newly synthesized polypeptides that contain inaccurate sequences
facilitate binding of ribosomes to mRNA

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