Translation and Regulation
The development of global regulatory systems in prokaryotes

determines the exact location of the cell on the globe
regulates many genes under varying environmental conditions
aids in DNA replication
determines the exact location of the replication site

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Translation and Regulation
The ribosome binding site

is located immediately upstream of the start codon
is located upstream of the promoter sequence
forms a stem-loop structure in the RNA
is more likely to be associated with an operon than with a gene encoding a single protein

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Translation and Regulation
The role of molecular chaperones is to

facilitate binding of RNA polymerase to DNA
aid a newly synthesized polypeptide in folding to its proper shape
degrade newly synthesized polypeptides that contain inaccurate sequences
facilitate binding of ribosomes to mRNA

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