Nucleic Acids
Because DNA is a highly charged polyanion, its stability to heat denaturation

decreases with increasing salt
is independent of G - C content
does not depend on hydrophobic interactions
increases with increasing salt

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Nucleic Acids
Thymidine

normally forms two hydrogen bonds with adenosine
can participate in hydrophobic interactions due to its methyl group
All of these
is replaced by uracil in RNA

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