Enzyme Reaction
An exergonic reaction is one that

gives off much heat
looses energy
requires energy to proceed
releases energy for work

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Enzyme Reaction
Hydrogen and oxygen release enormous amounts of energy when they react. Yet, hydrogen and oxygen can be mixed together in a balloon and nothing will happen. Why?

There must be contaminating elements in the balloon that prohibit the reaction from occurring
All of these
The energy of activation to form the transition-state complex is too high to allow the reaction to occur without assistance
Competitive inhibitors are blocking the reaction from occurring in the active site

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