Kushans were most probably one of the five branches of the Yuezhi confederation. Kujula Kadphises was the first Yuezhi chief and he laid the foundation of the Kushana Empire in India. He established his supremacy over Kabul, Kandahar, and Afghanistan.
The Nanda dynasty ruled in northern part of the Indian subcontinent during the 4th century BCE, and possibly during the 5th century BCE. In 326 BC, Alexander invaded India, after crossing the river Indus he advanced towards Taxila.