Antibody
Which of the following (s) is/are function (s) of Fc fragment of IgG?

All of these
It binds complement
It is related to passage of IgG across the placental barrier
It determines catabolic rate

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Antibody
Self reactive antibodies are not found in significant concentration in normal serum because

B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide
self reactive B cells are killed by CD8 T cells
self reactive B cells switch to IgA which is all secreted and not present in serum
it is impossible to generate a self-reactive antibody

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