Antibody
Which of the following (s) is/are function (s) of Fc fragment of IgG?

All of these
It determines catabolic rate
It is related to passage of IgG across the placental barrier
It binds complement

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Antibody
Self reactive antibodies are not found in significant concentration in normal serum because

self reactive B cells are killed by CD8 T cells
B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide
it is impossible to generate a self-reactive antibody
self reactive B cells switch to IgA which is all secreted and not present in serum

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