MS Power Point
The selected design template can be applied

All of the listed here
To all the new presentation you create
To all the slides
To current slide only

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MS Power Point
How to create additional Guide Lines?

by holding Ctrl key, click on existing Guide Line and drag
by holding Ctrl + Alt key, click on existing Guide Line and drag
by holding Alt key, click on existing Guide Line and drag
Additional Guide Lines cannot be created

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MS Power Point
The difference between Slide Design and Auto Content Wizard is

AutoContent Wizard is just the wizard version of Slide Design
Slide Design does not provide sample content but Auto Content Wizard provides sample content too!
Both are same
Slide Design asks your choice in steps but Auto Content Wizard does not let you make choices

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