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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The penicillin resistant to β-lactamases is

ampicillin
closacillin
penicillin-G
carbenicillin

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Antimicrobial Chemotherapeutic Agents
The most selective antibiotics are those that interfere with the synthesis of

bacterial DNA
bacterial plasma membrane
bacterial cell walls
bacterial RNA

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Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

cell wall synthesis
cell membrane function
protein synthesis
DNA function

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Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

inhibit DNA synthesis
inhibit folic acid synthesis
injury to the plasma membrane
inhibit protein synthesis

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Antimicrobial Chemotherapeutic Agents
Who developed the concept of specific toxicity?

Watson
Fleming
Pasteur
Ehrlich

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Antimicrobial Chemotherapeutic Agents
Quinolones are

broad-spectrum
bacteriostatic
penicillin derivatives
antimetabolites

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