DNA Structure and Replication
The melting of 40-45 bp at the oriC site of E. coli requires

DNA + ATP + HU + DNAb
DNA + ATP + HU + DNAb + DNAa + Pol III holoenzyme
DNA + ATP + HU
DNA+ ATP + HU + DNAb + DNAa

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DNA Structure and Replication
The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?

The RNase H domain of p66 causes error prone synthesis
AZT (zidovudine) is too expensive to be taken in effective doses
It has low affinity for the correct dNTP's
It lacks a proofreading exonuclease

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