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Synthesis of Therapeutic Agents

Synthesis of Therapeutic Agents
The gene coding for VP1 is cloned in

pMB 9
pUC 19
pUC 18
pBR 322

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Synthesis of Therapeutic Agents
Recombinant vaccine for HBV was produced by cloning viral genes in

plasmids
phagemids
autonomously replicating plasmid of yeast
cosmids

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Synthesis of Therapeutic Agents
Recombinant vaccine for Hepatitis B virus has been synthesized against which of the following antigen?

e antigen (HBeAg)
All of these
Viral surface antigen (HBsAg)
Viral core antigen (HBcAg)

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Synthesis of Therapeutic Agents
The promoter used for cloning HBV surface antigen is

β-galactosidase
alcohol dehydrogenase 1
polyhedrin
galactokinase

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Synthesis of Therapeutic Agents
Chemically synthesized DNA sequences for the two chains are separately inserted into the plasmid pBR 322 by the side of

β-Galactosidase
acid phosphatase
galactokinase
glucokinase

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Synthesis of Therapeutic Agents
The two chains of insulin can be separated by detaching it from β-galactosidase using

hydrogen chloride
cyanogen bromide
peptidase
protease

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