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DNA Structure and Replication

DNA Structure and Replication
Proteins involved in opening a replication bubble are

DNA topoisomerase
ligase
DNA helicases
single stranded binding proteins

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DNA Structure and Replication
What is the main damaging effect of UV radiation on DNA?

Single strand break
Dehydration
Formation of thymine dimers
Depurination

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DNA Structure and Replication
E.coli DNA polymerases II and III lack

partially 5' → 3' exonuclease activity
5' → 3' endonuclease activity
5' → 3' exonuclease activity
partially 5' → 3' endonuclease activity

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DNA Structure and Replication
There is a single origin for DNA replication in bacteria. How many origins of replication are found in the much larger genomes of eukaryotes such as mammals?

Thousands and tens of thousands
About 100
One
none of these

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DNA Structure and Replication
Which polymerase is active in DNA repairing

Polymerase I
none of these
Polymerase II
Polymerase III

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DNA Structure and Replication
In DNA, guanine pairs with

Adenine
Thymine
Cytosine
Uracil

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