Anti Bodies
Monoclonal antibodies were first produced by

Edward Jenner and Louis Pasteur
Georges Kohler and Cesar Milstein
Sarkar and Sommer
Selman Waksman

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Anti Bodies
A polyclonal antibody response

is produced by several B cells recognizing different pitopes on the same antigen
violates clonal selection
occurs during the lag phase of the immune response
is produced only in response to polymeric antigens

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Anti Bodies
Papain digest IgG into

two Fab fragments and two Fc fragments
three Fab fragments and two Fc fragments
three Fab fragments and three Fc fragments
two Fab fragments and one Fc fragment

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Anti Bodies
The immunoglobulin fold is

a β-barrel composed of a three- and a four-stranded antiparallel β-sheet
both (a) and (b)
found only in IgG molecules
found six times in the IgG molecule

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