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Disorders in Biotechnology

Disorders in Biotechnology
Klinefelter syndrome is a manifestation of which chromosome aneuploidy?

None of these
XXX
XYY
XXY

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Disorders in Biotechnology
What is the defective enzyme in the glycogen storage Von Gierke's disease?

Glucose-6-phosphatase
Phosphorylase
Phosphofructokinase
None of these

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Disorders in Biotechnology
The disorder in which of the following may cause "Ehlers-Danlos Syndrome"?

Globulin protein
Fibrin protein
Dlashin protein
Collagen protein

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Disorders in Biotechnology
Which of the modification in hemoglobin is the cause of sickle cell anemia?

Replacement of the B chain by D chain
None of these
A deletion in the beta chain
A mutation in the beta chain

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Disorders in Biotechnology
During sickle cell anemia which of the following takes place?

Valine change to glutamine
Glutamic acid change to aspartic acid
Aspartic acid change to glutamic acid
Glutamine change to valine

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Disorders in Biotechnology
Methotrexate is toxic to human cells because it inhibits

formation of CTP from UTP
reduction of H2 folate to H4 folate
None of these
synthesis of PRPP

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