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Disorders in Biotechnology

Disorders in Biotechnology
Klinefelter syndrome is a manifestation of which chromosome aneuploidy?

XXX
XXY
XYY
None of these

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Disorders in Biotechnology
A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause

Lesch- Nyhan syndrome
Kleinefelter's syndrome
Gaucher's disease
Ehlers-Danlos syndrome

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Disorders in Biotechnology
During sickle cell anemia which of the following takes place?

Valine change to glutamine
Glutamine change to valine
Glutamic acid change to aspartic acid
Aspartic acid change to glutamic acid

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Disorders in Biotechnology
If the RBC of human were kept in 0.9% NaCl solution, what sort of change will occur to RBC?

RBC will destroy
Cell will Burst
No change to RBC
Cell will shrink

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Disorders in Biotechnology
Methotrexate is toxic to human cells because it inhibits

synthesis of PRPP
reduction of H2 folate to H4 folate
formation of CTP from UTP
None of these

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Disorders in Biotechnology
What is the defective enzyme in the glycogen storage Von Gierke's disease?

Phosphofructokinase
Glucose-6-phosphatase
Phosphorylase
None of these

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