DNA Replication
During DNA replication in prokaryotes, synthesis begins on the circular chromosome

at any stretch of DNA that is high in AT pairs
always at the same place
randomly on the chromosome
at the promoter

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DNA Replication
Proofreading activity to maintain the fidelity of DNA synthesis

is a function of the 3'-5' exonuclease activity of the DNA polymerases
occurs in prokaryotes but not eukaryotes
requires the presence of an enzyme separate from the DNA polymerases
occurs after the synthesis has been completed

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DNA Replication
The replication of chromosomes by eukaryotes occurs in a relatively short period of time because

each chromosome contains multiple replicons
the eukaryotes have more amount of DNA for replication
eukaryotic DNA is always single stranded
the eukaryotic replication machinery is 1000 times faster than the prokaryotes

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