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DISORDERS IN BIOTECHNOLOGY

Disorders in Biotechnology
During sickle cell anemia which of the following takes place?

Glutamine change to valine
Aspartic acid change to glutamic acid
Valine change to glutamine
Glutamic acid change to aspartic acid

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Disorders in Biotechnology
Methotrexate is toxic to human cells because it inhibits

synthesis of PRPP
None of these
formation of CTP from UTP
reduction of H2 folate to H4 folate

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Disorders in Biotechnology
What is the defective enzyme in the glycogen storage Von Gierke's disease?

Phosphorylase
Glucose-6-phosphatase
Phosphofructokinase
None of these

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Disorders in Biotechnology
A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause

Ehlers-Danlos syndrome
Lesch- Nyhan syndrome
Gaucher's disease
Kleinefelter's syndrome

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Disorders in Biotechnology
Which of the following sets belongs to a distinct class or category?

Ribose, sucrose, glucose, fructose
Oils, sterols, waxes, fats
Sterols, waxes, fatty acids, amino acids.
Nucleotide, nucleoside, nucleus, DNA

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