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DISORDERS IN BIOTECHNOLOGY

Disorders in Biotechnology
During sickle cell anemia which of the following takes place?

Glutamine change to valine
Valine change to glutamine
Glutamic acid change to aspartic acid
Aspartic acid change to glutamic acid

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Disorders in Biotechnology
Methotrexate is toxic to human cells because it inhibits

None of these
formation of CTP from UTP
reduction of H2 folate to H4 folate
synthesis of PRPP

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Disorders in Biotechnology
What is the defective enzyme in the glycogen storage Von Gierke's disease?

Phosphorylase
None of these
Glucose-6-phosphatase
Phosphofructokinase

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Disorders in Biotechnology
A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause

Ehlers-Danlos syndrome
Lesch- Nyhan syndrome
Kleinefelter's syndrome
Gaucher's disease

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Disorders in Biotechnology
Which of the following sets belongs to a distinct class or category?

Oils, sterols, waxes, fats
Nucleotide, nucleoside, nucleus, DNA
Sterols, waxes, fatty acids, amino acids.
Ribose, sucrose, glucose, fructose

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