Operating System (OS)
The disadvantages of "Compile and Go" loading scheme is (are):

All of these
it is very difficult to handle multiple segments, especially if the source programs are in different languages, and to produce orderly modular programs.
None of these
it is necessary to retranslate the user's program deck every time it is run.
a portion of memory is wasted because the core occupied by the assembler is unavailable to the object program.

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Operating System (OS)
System generation:

is always quite simple
None of these
requires extensive tools to be understandable
varies in difficulty between systems
is always very difficult

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